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Sarah M. Wilson, Ph.D.

Translational Scholar
Neuroscience Strategic Research Initiative
STARK Neurosciences Research Institute
Indiana University School of Medicine

Education/Training
B.S., Psychology, Indiana University, Bloomington (2009)

Ph.D., Medical Neuroscience, Indiana University School of Medicine (2014)


Research
After recently completing my doctoral work on molecular mechanisms underlying mossy fiber sprouting following traumatic brain injury, I accepted a position as a Translational Scholar through the Neuroscience Strategic Research Initiative, a joint venture between IU School of Medicine and IU Health, under Dr. Gerry Oxford and Dr. Nicholas Barbaro.  In this role, I am responsible for the identification and maintenance of collaborative opportunities between clinical and research faculty within the Neuroscience field.  Currently I am focusing on three keys areas (Neurotrauma, Alzheimer’s Disease, and Epilepsy) in which strengths in research and clinical care can be combined to ease the transition of ideas from bedside to bench and back.

Search for Dr. Wilson on PubMed

Recent and Relevant Publications

  1. Wilson SM, Moutal A, Melemedjian OK, Wang Y, Ju W, François-Moutal L, Khanna M, Khanna R. The functionalized amino acid (S)-Lacosamide subverts CRMP2-mediated tubulin polymerization to prevent constitutive and activity-dependent increase in neurite outgrowth. Frontiers in Cellular Neuroscience. 2014 Jul 24;8:196.

  2. Wilson SM, Khanna R. Specific Binding of Lacosamide to Collapsin Response Mediator Protein 2 (CRMP2) and Direct Impairment of its Canonical Function: Implications for the Therapeutic Potential of Lacosamide. Molecular Neurobiology. 2014 Jun 20 [Epub ahead of print].

  3. Wilson SM, Yeon, SK, Yang XF, Park KD, Khanna R. Differential regulation of collapsin response mediator protein 2 (CRMP2) phosphorylation by GSK3β and CDK5 following traumatic brain injury. Frontiers in Cellular Neuroscience. 2014 May 28;8:135.

  4. Wilson SM, Schmutzler BS, Brittain JM, Dustrude ET, Ripsch MS, Pellman JJ, Yeum TS, Hurley JH, Hingtgen CM, White FA, Khanna R. Inhibition of transmitter release and attenuation of AIDS therapy-induced and tibial nerve injury-related painful peripheral neuropathy by novel synthetic Ca2+ channel peptides. Journal of Biological Chemistry. 2012 Oct 12;287(42):35065-77.

  5. Wilson SM, Xiong W, Wang Y, Ping X, Head JD, Brittain JM, Gagare PD, Ramachandran V, Jin X, and Khanna R.  Prevention of posttraumatic axon sprouting by blocking CRMP2-mediated neurite outgrowth and tubulin polymerization. Neuroscience. 2012 Mar; 210: 451-66.

  6. Wilson SM, Brittain JM, Piekarz AD, Ballard CJ, Ripsch MS, Cummins TR, Hurley JH, Khanna M, Hammes NM, Samuels BC, White FA, Khanna R.  Further insights into the antinociceptive potential of a peptide disrupting the N-type calcium channel-CRMP-2 signaling complex.  Channels (Austin).  2011 Sep 1;5(5).

  7. Brittain JM, Duarte DB, Wilson SM, Zhu W, Ballard C, Johnson PL, Liu N, Xiong W, Ripsch MS, Wang Y, Fehrenbacher JC, Fitz JD, Khanna M, Park CK, Schmutzler BS, Cheon BM, Due MR, Brustovetsky T, Ashpole NM, Hudmon A, Meroueh SO, Hingtgen CM, Brustovetsky N, Ji RR, Hurley JH, Jin X, Shekhar A, Xu XM, Oxford GS, Vasko MR, White FA, Khanna R.  Suppression of inflammatory and neuropathic pain by uncoupling CRMP-2 from the presynaptic Ca2+ channel complex. Nature Medicine.  2011 Jun 5;17(7):822-9.

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