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About

Welcome to the Spinal Cord and Brain Injury Research Group at Indiana University School of Medicine. This is an exciting time for us as our group is relatively new to the School of Medicine and is in the midst of a vigorous expansion phase.

We are located within the Stark Neuroscience Research Institute on the 5th floor of the newly completed Neuroscience Research building at 320 West 15th Street, adjacent to Goodman Hall. Our group is strongly supported by the Stark Neurosciences Research Institute (SNRI), Department of Neurological Surgery, and Department of Anatomy and Cell Biology. The group was started in September 2007 with the recruitment of Dr. Xiao-Ming Xu as the first Scientific Director and Mari Hulman George Professor of Neurological Surgery. In December 2008, Dr. Jinhui Chen, an expert in hippocampal neurogenesis following traumatic brain injury (TBI) was recruited as an Assistant Professor of Neurological Surgery and Principal Investigator. In January 2009, Dr. Xiaoming Jin, the third member of the group whose expertise is in cortical neural plasticity after epilepsy and TBI, was recruited as an Assistant Professor of Anatomy and Cell Biology and Principal Investigator. Currently, we are actively recruiting the fourth faculty member with expertise in traumatic spinal cord injury (SCI). With recruitment of additional members from the School of Medicine, we now have a research team of 14 principal investigators, 3 clinical investigators, 1 associate investigator and 1 adjunct investigator. Additionally, the group is filled with energetic graduate students, postdoctoral fellows, and research staff. The growth and development of our group is guided by a Strategic Planning Committee formed by Drs. Gerry Oxford, (now former) Executive director of SNRI, Paul Nelson, (now former) Chairman of Department of Neurological Surgery, and Xiao-Ming Xu.

Our group is a highly focused research team studying traumatic spinal cord and brain injuries. These injuries are a leading cause of disability in children, adults, and military personnel, and represent a significant socioeconomic burden. In the United States, approximately 11,000 SCI and 1,400,000 TBI new cases occur each year, and 250,000 and 5,000,000 people currently live with disabilities resulting from SCI and TBI, respectively. The mission of our group is to "understand molecular mechanisms underlying traumatic spinal cord and brain injuries and develop innovative repair strategies that can be translated into clinical treatments of these diseases in a timely and responsive fashion."  Our scientists are working extremely hard to realize this mission.  
    
Our team has three functional units, i.e. basic scientists, clinician scientists, and core facilities. The basic scientists, with expertise from cellular and molecular biology to animal models and functional assessments, will generate optimal repair strategies in a complementary and collaborative manner. The clinician scientists, with experience in patients with SCI and TBI, will be responsible for translating promising research results, obtained by basic scientists, into pre-clinical and clinical trials. The core facilities include a Surgical Core and Behavioral Core with an array of standardized injury models and functional assessments which insure the quality, reproducibility, and efficiency of our research.

Please contact us if you are interested in joining our research team, collaborating with us, or supporting our research.

Xiao-Ming Xu, M.D., Ph.D.
Mari Hulman George Professor and Scientific Director

Stark Neurosciences Research Institute | Neuroscience Research Building | 320 West 15th Street | Indianapolis, IN 46202 | Phone: (317) 278-5848 | FAX: (317) 231-0203