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Positions in Neuroscience at IU School of Medicine

Post-Doctoral Position in Stem Cell Biology

A post-doctoral position is available immediately to study genetic inner ear disorders with human pluripotent stem cells in 3D culture (Koehler et al., Nature 2013; Liu et al., Nature Commun 2016).  The goals of this project are to recapitulate pathogenesis of monogenic inner ear disorders, such as CHARGE Syndrome and DFNA36 deafness, and elucidate the mechanisms responsible for the clinical phenotypes associated with patient-specific genetic mutations.  Our ultimate goal is to identify therapeutic targets for delaying or reversing the pathological conditions for these inner ear maladies.

Applicants should have a Ph.D. degree or equivalent in biomedical sciences.   Previous research experience in CRISPR/Cas9, confocal microscopy or live cell imaging is highly desirable, but not required. The starting date is flexible.

Located in downtown Indianapolis, Indiana University School of Medicine (IUSM) is the second largest medical school in the US and boasts an outstanding intellectual atmosphere and core research facilities.  IUSM was nationally ranked in the Top 30 Best Places to Work for Post-docs.

If interested, please send a CV, brief description of research experience & interest and contact information of three references to: Dr. Eri Hashino (ehashino@iupui.edu), Ruth C. Holton Professor and Vice Chair for Research, Department of Otolaryngology – Head & Neck Surgery, Indiana University School of Medicine. 

Indiana University is an EEO/AA employer, M/F/D.

 


 

The laboratory of Dr. Cristian Lasagna-Reeves seeks a Research Technician I (RS07) to work on a project focused on the mechanism of aggregation of tau protein in neurodegeneration using cell models and the characterization of the phenotype of mouse models of Alzheimer’s disease and Frontotemporal Dementia. The candidate will conduct a variety of experiments with clearly established methodologies, including but not limited to: i) neural cell line and primary neural culture, ii) mouse colony maintenance, including recordkeeping, breeding, genotyping, and iii) protein assays, including ELISA and western blot. In addition, the applicant will be expected to perform daily operations of the lab, e.g. request quotes and place orders, maintenance of lab equipment and reagent inventories.

To apply send your resume and three references with contact information to:

Cristian Lasagna-Reeves, Ph.D.: clasagna@iu.edu

Salary will commensurate with experience. Indiana University is an EEO/AA employer, M/F/D.

 


 

Postdoctoal Fellow Position for the Indiana University (IU)/Jackson Laboratory (JAX) Alzheimer’s Disease Precision Models Center (IU/JAX ADPMC).  The Center is a multidisciplinary team at the forefront of translational Alzheimer’s disease research, using cutting edge technology to develop, validate and disseminate new, precise animal models of Alzheimer’s disease (AD). The Center is looking for an enthusiastic and highly motivated young scientist interested in working with a multidisciplinary team. 

Requirements
The candidate should have an interest in neurodegenerative disease. He or she must possess a Ph.D. or foreign certificate equivalent to a doctoral degree in biomedical research, completed within four years prior to the date of application, as well as documented experience and skills in neurochemistry, molecular neurobiology, and neuropharmacology research. The successful candidate should have strong competence to work independently, and strong abilities in teamwork and scientific cooperation with other postdocs and students in the laboratory. Applicants should have excellent verbal and written English skills.

The application should include the following documents, in English:

•A short cover letter describing the applicant's interest in the position (maximum one page).

•Curriculum vitae and qualifications including academic degree, thesis title, date of defense, and names and affiliations of the mentors/supervisors.

•A complete list of publications.

•A summary of current work (maximum one page).

•Signed letters of recommendation and contact information from two or three references.

•Application should be sent to: stark1@iupui.edu

IUSM is an EEO/AA Employer, M/F/D.


Research Associate Position for the Indiana University (IU)/Jackson Laboratory (JAX) Alzheimer’s Disease Precision Models Center (IU/JAX ADPMC).  The Center is a multidisciplinary team at the forefront of translational Alzheimer’s disease research, using cutting edge technology to develop, validate and disseminate new, precise animal models of Alzheimer’s disease (AD). The Center is looking for an enthusiastic and highly motivated research associate interested in working with a multidisciplinary team. 

The research associate will assist with the research conducted in the IU/JAX ADPMC at many levels. The incumbent will be expected to have a high degree of technical expertise. The research associate will be proficient in the scientific techniques used in the lab, and will develop and maintain SOPs and train lab members in their use. The incumbent will also spend a proportion of time leading experiments and analyzing data, writing manuscripts, scientific reports, and disseminating information, and will be expected to play a role in guiding the scientific direction of the IU/JAX ADPMC including grant writing.

The research associate will interact with and help to oversee trainees, and will work in collaboration with other lab staff, postdoctoral fellows and students.

Requirements
The candidate should have an interest in neurodegenerative disease.

Education:

•Ph.D. in life sciences or equivalent.

Experience:

•Three years postdoctoral training including experience in molecular and cellular analysis of brain tissue and experience in behavioral analysis of rodents.

•Experience training students on lab procedures, equipment and safety.

•Experience managing multiple research projects in a highly productive lab environment.

•Must have a strong publication record including first author publications in high impact journals in the area of brain function.

Knowledge, Skills and Abilities:

Demonstrated knowledge of the utilization of animal research models and handling.

•Advanced computer skills and software application.

•Proven ability to multi-task and prioritize with an eye to consistently producing high-quality work and meeting deadlines in a demanding environment.

•Excellent communication skills to effectively interact with technical and non-technical users.

•Well-developed presentation skills with demonstrated ability to conduct training sessions and instruct others both in small and large groups in formal and informal settings.

•Excellent written communication skills with a demonstrated ability to complete detailed analytics and reports.

•Sound knowledge of associated risks in a research environment and laboratory safety regulations.

•Ability to perform both standard and complex laboratory procedures with accuracy, precision and reliability.

•Possess a reputation for resourcefulness with the ability to research/investigate issues and resolve problems with a strong sense of accountability and initiative.

•Strong record of teamwork with the motivation and ability to work independently with little or no supervision.

•Application should be sent to: stark1@iupui.edu

IUSM is an EEO/AA Employer, M/F/D.


Postdoctoral Scientist Position in Neurodegeneration and Axonal Transport

Stark Neurosciences Research Institute
Indiana University School of Medicine

The laboratory of Dr. Elliot Androphy seeks a postdoctoral fellow to investigate the role of axonal transport in spinal muscular atrophy and other motoneuron degenerative diseases.

The fellow will collaboratively design projects, develop novel techniques, present findings at conferences, draft manuscripts, and participate in education of students. Experience with imaging techniques, molecular biology, and transgenic animal models of neurologic disease is a plus.

To apply, please send a cover letter describing your research interests/relevant background, a curriculum vitae, 3 references, and relevant reprints/preprints of research articles to:  

Elliot Androphy M.D.: eandro@iu.edu

Salary will be commensurate with experience.  IU is an EEO/AA Employer, M/F/D. 


Postdoctoral Position in Spinal Cord Injury and Brain Injury Research

Highly motivated individuals are invited for two postdoctoral positions immediately available in the Laboratory of Dr. Xiao-Ming Xu at Spinal Cord and Brain Injury Research Group (SCBIRG), Stark Neurosciences Research Institute (SNRI), and Department of Neurological Surgery at Indiana University School of Medicine. Applicants should have a Ph.D. or M.D. in neuroscience or a related discipline and are expected to develop a strong research project in spinal cord injury (SCI) or traumatic brain injury (TBI) research. Candidates with expertise or interest in animal models of SCI/TBI, neuroprotection, cell transplantation, axonal regeneration, cellular and molecular biology, and genetics are particularly encouraged to apply. Salary will be competitive and based upon qualifications and experience. Applications will be accepted until the position is filled.

To apply, please submit a curriculum vitae, and names of three references to:

Prof. Xiao-Ming Xu

Scientific Director, SCBIRG

Stark Neurosciences Research Institute

Indiana University School of Medicine

320 W. 15th Street, NB 500E

Indianapolis, IN 46202

E-mail: xu26@iupui.edu

Indiana University is an equal opportunity and affirmative action employer, and a provider of American Disabilities Act services. All qualified applicants will receive consideration for employment without regard to age, ethnicity, color, race, religion, sex, sexual orientation or identity, marital status, national origin, disability status, or protected veteran status. Indiana University does not discriminate on the basis of sex in its educational programs and activities, including employment and admission, as required by Title IX. Questions or complaints regarding Title IX may be referred to the U.S. Department of Education Office for Civil Rights or the university Title IX coordinator. See Indiana University’s Notice of Non-Discrimination, which includes contact information.


The Department of Neurological Surgery at Indiana University School of Medicine has an immediate opening for an outstanding applicant for a full-time Research Associate position.  The primary activity of this Research Associate will be to conduct basic/translational research in brain tumor immunotherapy working on developing Dendritic cell and T-cell based immunotherapy for malignant brain tumors while studying the mechanisms of immune response associated with brain tumor.  Focus includes tumor associated antigen presentation, T-cell response and plasticity and modifying DCs and T-cells.

To be considered, applicants are required to have a Ph.D. in cancer immunology or in a closely related field and should have experience and proficiency in immunological assays, DC and T-cell culture, T-cell engineering, handling mice and basic molecular biology skills.  The successful candidate should be motivated and have future plans of pursuing independent research career, must be able to perform self-directed work, and possess excellent collaborative/communication skills with demonstrated experience in successful manuscript writing and publications.

Applicant must be currently in US and be able to start right away. Compensation is dependent upon qualifications.  Review of applicants will continue until the position is filled.  Applicants should submit a cover letter indicating their area of interest, complete curriculum vitae and three letters of reference to:

ATTN: Dr. Mahua Dey
Department of Neurological Surgery
980 W. Walnut Street, R3-C514
Indianapolis, IN 46202
mdey@iu.edu

Indiana University is an Affirmative Action/Equal Opportunity Institution M/F/D/V


Research Associate Position in Neurological Surgery - Spinal Cord Brain Injury Research Group - Stark Neurosciences Research Institute

The Department of Neurological Surgery at Indiana University School of Medicine is seeking applicants for 2 full-time Research Associate positions.  The primary activity of this Research Associate will be to conduct research in association with a highly dynamic and collaborative team working on understanding the neuronal mechanisms of spinal cord injury and regeneration.  Focus includes spinal cord injury.

To be considered, applicants are required to have a Ph.D. in neuroscience or in a closely related field and should have experience in spinal cord injury models, neuronal and glial cell culture, cell transplantation, anatomical tracing and behavioral assessments of rats and mice.  The successful candidate must be able to perform self-directed work, and possess excellent collaborative skills with demonstrated experience in oral and written presentation of research findings.

Compensation is dependent upon qualifications.  Review of applicants will continue until the position is filled.  Applicants should submit a cover letter indicating their area of interest, complete curriculum vitae and three letters of reference to:

ATTN: Dr. Xiao-Ming Xu

Department of Neurological Surgery

Indiana University School of Medicine

320 W. 15th Street, Suite 500E

Indianapolis, IN 46202

*Indiana University is an Affirmative Action/Equal Opportunity Institution M/F/D/V


Postdoctoral Scientist Position in Redox Regulation of Microglia Biology and Neuropathology

Stark Neurosciences Research Institute
Indiana University School of Medicine

The Laboratory of Dr. Michelle L. Block is currently accepting applications for a postdoc focused on discovering the molecular mechanisms underlying the pathology of the brain’s innate immune cells, microglia, that drive chronic central nervous system (CNS) damage.  The position will explore how reactive oxygen species derived from ongoing neurodegenerative disease processes, environmental exposures, and aging reprogram microglia to become a chronically neurotoxic/deleterious phenotype.  Primary cell culture, cell lines, and mouse models of CNS pathology in Parkinson’s disease, Gulf War Illness, air pollution exposure, and Alzheimer’s disease will be routinely used along with molecular biology, histochemistry, immuno-spin trapping/reactive oxygen species assessment, unbiased stereology,  and imaging techniques (confocal, 2-photon, fluorescence, and bright field microscopy) to address these key questions.

To apply, please send a cover letter describing your research interests/relevant background, a curriculum vitae, 3 references, and relevant reprints/preprints of research articles to:   Michelle L. Block, Ph.D.  Department of Anatomy & Cell Biology, mlblock@iupui.edu

The successful applicant will be highly motivated and have a Ph.D. in Neuroscience or a related scientific field.   Strong experience with imaging techniques (confocal and 2-photon) and molecular biology is a plus.  The candidate will manage projects, develop novel techniques, present findings at conferences, write manuscripts, and contribute to grant application preparation, where training/mentoring/active collaboration for these responsibilities is designed to advance scientific and career growth.  Salary will be commensurate with experience.  IU is an EEO/AA Employer, M/F/D.


Senior Physician-Scientist Position in Neurodegeneration Research - Neuroscience Center

The Indiana University School of Medicine, in partnership with Indiana University Health, is undertaking a major expansion of neuroscience research and research facilities at its campus in Indianapolis.  A recently completed Neuroscience Center complex serves as the focal point for recruiting outstanding investigators and physicians at all levels over the next several years. 

The Neuroscience Center, in partnership with the Indiana Alzheimer’s Disease Center (IADC) and the Stark Neurosciences Research Institute (SNRI) announces a search for an accomplished senior level investigator for a position at the rank of Associate or Full Professor to be a team leader in a multi-faculty translational research group in neurodegenerative disorders.  We seek applications from individuals with exceptional and well-funded research programs in any area of neurodegenerative disorders, particularly with direct translational potential.  The selected candidate will have the opportunity to participate in hiring of additional faculty investigators and develop an internationally prominent research program.  Of particular interest are candidates who combine innovative imaging, genomic, biomarker or connectomic approaches in human clinical subjects and animal models to address fundamental questions in Alzheimer’s Disease or related dementias.

Primary departmental affiliation is anticipated to be in Neurology, Psychiatry, or Pathology although appointments in other departments can be negotiated by mutual interest.  An M.D. and/or Ph.D. degree and strong evidence of continuous productivity and grant support are required.  A competitive initial support package will include ample start-up funds and laboratory space as needed and access to exceptional core research facilities for animal and human imaging, genomics, chemical biology, transgenics, and computational biology and bioinformatics.  Interested individuals should send a curriculum vita, a research prospectus, and the names and addresses of 5 references.  Application materials will only be accepted in electronic format (PDF) by submission as an attachment to stark1@iupui.edu with the Subject: Neurodegeneration Faculty Search.   IU is an EEO/AA Employer, M/F/D.


Senior Faculty Position in Developmental Neuroscience

Stark Neurosciences Research Institute
Wells Center for Pediatric Research
Indiana University School of Medicine

The Indiana University School of Medicine, in partnership with Indiana University Health, is undertaking a major expansion of neuroscience research and research facilities at its campus in Indianapolis.  The Paul & Carole Stark Neurosciences Research Institute (SNRI) in partnership with the Herman B. Wells Center for Pediatric Research announces a search for an accomplished senior level investigator for a position at the rank of Associate or Full Professor to direct and expand a multi-faculty research group in neurodevelopment and regeneration.  Individuals with exceptional and well-funded research programs in any area of developmental neuroscience, particularly with direct translational potential, will have the opportunity to participate in hiring of additional junior and mid-career investigators and develop an internationally prominent research group.  Of particular interest are candidates who combine cellular, molecular or genetic approaches to investigate fundamental questions in human developmental disorders.  Researchers employing interdisciplinary approaches including advanced imaging, structural biology, or electrophysiology are encouraged to apply.  Primary departmental affiliation is anticipated to be in Pediatrics, Psychiatry, Neurology, or Genetics although appointments in other departments can be negotiated by mutual interest.  An M.D. and/or Ph.D. degree and strong evidence of continuous productivity and grant support are required.  A competitive initial support package will include ample start-up funds and laboratory space in a new research building and access to exceptional core research facilities for animal and human imaging, molecular biology, chemical biology, transgenics, and computational biology and bioinformatics.  More information about the SNRI (snri.iusm.iu.edu) and the Wells Center (wellscenter.iupui.edu) can be found on our websites.  Interested individuals should send a curriculum vita, a research prospectus, and the names and addresses of 5 references.  Application materials will only be accepted in electronic format by submission to the attention of Dr. Bruce Lamb, Executive Director, Stark Neurosciences Research Institute, IU School of Medicine at stark1@iupui.edu.  IU is an EEO/AA Employer, M/F/D.

Stark Neurosciences Research Institute | Neuroscience Research Building | 320 West 15th Street | Indianapolis, IN 46202 | Phone: (317) 278-5848 | FAX: (317) 231-0203